About the Lab

As a part of the University of Pennsylvania’s Microbiology Department, the Cherry Lab is interested in genetic and mechanistic studies of viral-host interactions. The Lab performs a wide array of cell-based screens in insect and human cells using emerging arboviruses, including chikungunya and zika virus.Our team also studies intestinal infection in Drosophila, where the role of the microbiota in protection from enteric arboviral infections is dissected. Projects include understanding how dysbiosis impacts susceptibility and discovering the bacterial products that impact infection.Human cells are used to dissect the mechanisms involved in viral RNA recognition and RNA decay, and the mechanisms by which nutrient signaling and autophagy impact viral infection. Our students are encouraged to explore additional projects in the areas of viral-host interactions and innate immunity.

NEWS
NOV
2018
The Cherry Lab is happy to welcome our new post-doc, Billy Palmer. Billy recently finished his PhD at the University of Edinburgh studying the evolution of RNA interference pathways and Drosophila immune responses during DNA virus infection. He is broadly interested in innate immunity, especially in the context of host-virus coevolution. He joined our staff in October 2018.
NOV
2018
Cherry Lab Graduate student Megha Basavappa won an award, Best Talk, at the Immunology Graduate Group Annual Retreat. Congratulations to Megha!
NOV
2018
Post-doc researcher, Yuan Liu, recently has his paper “Zika virus infection activates sting-dependent antiviral autophagy in the Drosophila brain” published in the September 2018 edition of “Autophagy.” To read his paper, please visit the “Publications” page in this site.